Cellosaurus logo
expasy logo

Cellosaurus MOC2LN (CVCL_ZD38)

[Text][XML][JSON]
Cell line name MOC2LN
Accession CVCL_ZD38
Resource Identification Initiative To cite this cell line use: MOC2LN (RRID:CVCL_ZD38)
Comments Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gln61His (c.183A>T); Zygosity=Unspecified (from autologous cell line MOC2).
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Glu225Ter; Zygosity=Unspecified (from autologous cell line MOC2).
Disease Squamous cell carcinoma of the mouse oral cavity (NCIt: C23049)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 Cxcr3-/-.
Originate from same individual CVCL_ZD33 ! MOC2
Sex of cell Female
Category Cancer cell line
Publications

PubMed=24668645; DOI=10.1158/1078-0432.CCR-14-0205; PMCID=PMC4096804
Michael D. Onken, Ashley E. Winkler, Krishna-Latha Kanchi, Varun Chalivendra, Jonathan H. Law, Charles G. Rickert, Dorina Kallogjeri, Nancy P. Judd, Gavin P. Dunn, Jay Francis Piccirillo, James S. Lewis Jr. ...Show all 13 authors... , Elaine R. Mardis, Ravindra Uppaluri; Show fewer authors
A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.
Clin. Cancer Res. 20:2873-2884(2014)

PubMed=25729643; DOI=10.1016/j.gdata.2014.11.006; PMCID=PMC4340082
Varun Chalivendra, Krishna-Latha Kanchi, Michael D. Onken, Ashley E. Winkler, Elaine R. Mardis, Ravindra Uppaluri;
Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer.
Genom. Data 3:61-62(2015)

Cross-references
Encyclopedic resources Wikidata; Q98127277
Gene expression databases GEO; GSM1213097
GEO; GSM1213098
GEO; GSM1213099
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number9