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Cellosaurus MLEC-Ext1-/- (CVCL_ZC96)

[Text version]
Cell line name MLEC-Ext1-/-
Synonyms MLEC-Ext1 null; Mouse Lung Endothelial Ext1-/-
Accession CVCL_ZC96
Resource Identification Initiative To cite this cell line use: MLEC-Ext1-/- (RRID:CVCL_ZC96)
Comments Knockout cell: Method=Floxing/Cre recombination; MGI; MGI:894663; Ext1.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Proteomics; PTM; Phosphorylation; Quantitative.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Endothelial cell of lung; CL=CL_1001567.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Ext1f/f x C57BL/6J.
Hierarchy Parent: CVCL_ZC95 (MLEC-Ext1f/f)
Sex of cell Sex unspecified
Age at sampling 8W
Category Transformed cell line
Publications

PubMed=23649490; DOI=10.1074/mcp.M112.026609; PMCID=PMC3734577
Qiu H., Jiang J.-L., Liu M., Huang X., Ding S.-J., Wang L.-C.
Quantitative phosphoproteomics analysis reveals broad regulatory role of heparan sulfate on endothelial signaling.
Mol. Cell. Proteomics 12:2160-2173(2013)

PubMed=30377379; DOI=10.1038/s41592-018-0189-6; PMCID=PMC6214364
Qiu H., Shi S.-S., Yue J.-W., Xin M., Nairn A.V., Lin L., Liu X., Li G., Archer-Hartmann S.A., dela Rosa M., Galizzi M., Wang S.-C., Zhang F., Azadi P., van Kuppevelt T.H., Cardoso W.V., Kimata K., Ai X.-B., Moremen K.W., Esko J.D., Linhardt R.J., Wang L.-C.
A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Nat. Methods 15:889-899(2018)

Cross-references
Cell line collections (Providers) Kerafast; EGA314
Encyclopedic resources Wikidata; Q98127249
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number8