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Cellosaurus MLEC-Ext1f/f (CVCL_ZC95)

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Cell line name MLEC-Ext1f/f
Synonyms Mouse Lung Endothelial Ext1f/f
Accession CVCL_ZC95
Resource Identification Initiative To cite this cell line use: MLEC-Ext1f/f (RRID:CVCL_ZC95)
Comments Characteristics: Control cell line for MLEC-Ext1-/- (Cellosaurus=CVCL_ZC96).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Proteomics; PTM; Phosphorylation; Quantitative.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Endothelial cell of lung; CL=CL_1001567.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Ext1f/f x C57BL/6J.
Hierarchy Children:
CVCL_ZC96 (MLEC-Ext1-/-)
Sex of cell Sex unspecified
Age at sampling 8W
Category Transformed cell line
Publications

PubMed=23649490; DOI=10.1074/mcp.M112.026609; PMCID=PMC3734577
Hong Qiu, Jun-Lin Jiang, Miao Liu, Xin Huang, Shi-Jian Ding, Lian-Chun Wang;
Quantitative phosphoproteomics analysis reveals broad regulatory role of heparan sulfate on endothelial signaling.
Mol. Cell. Proteomics 12:2160-2173(2013)

PubMed=30377379; DOI=10.1038/s41592-018-0189-6; PMCID=PMC6214364
Hong Qiu, Song-Shan Shi, Jing-Wen Yue, Meng Xin, Alison V. Nairn, Lei Lin, Xin-Yue Liu, Guo-Yun Li, Stephanie A. Archer-Hartmann, Mitche dela Rosa, Melina Galizzi ...Show all 22 authors... , Shun-Chun Wang, Fu-Ming Zhang, Parastoo Azadi, Toin H. van Kuppevelt, Wellington Veras Cardoso, Koji Kimata, Xing-Bin Ai, Kelley W. Moremen, Jeffrey David Esko, Robert John Linhardt, Lian-Chun Wang; Show fewer authors
A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Nat. Methods 15:889-899(2018)

Cross-references
Cell line collections (Providers) Kerafast; EGA315
Encyclopedic resources Wikidata; Q98127248
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number9