Cellosaurus cell line AALEB (CVCL

Cellosaurus AALEB (CVCL_ZC94)

Cross-references
Cell line name	AALEB
Accession	CVCL_ZC94
Resource Identification Initiative	To cite this cell line use: AALEB (RRID:CVCL_ZC94)
Comments	Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Lung, bronchus, tracheobronchial epithelium; UBERON=UBERON_0008397. Cell type: Epithelial cell of tracheobronchial tree; CL=CL_0002202.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Transformed cell line
Web pages	Provider; UNC OTC; 19-0116; https://web.archive.org/web/20200120011157/http://technologies.unc.edu/technologies/19-0116_cell-line-aaleb
Publications	PubMed=12085236; DOI=10.1038/sj.onc.1205550 Ante Sven Lundberg, Scott H. Randell, Sheila A. Stewart, Brian Elenbaas, Kimberly A. Hartwell, Mary W. Brooks, Mark Daniel Fleming, John C. Olsen, Scott W. Miller, Robert Allan Weinberg, William Chun Hahn; Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene 21:4577-4586(2002) PubMed=15804356; DOI=10.1186/1465-9921-6-26; PMCID=PMC1087506 Qi Wu, Zhong Lu, Margrith W. Verghese, Scott H. Randell; Airway epithelial cell tolerance to Pseudomonas aeruginosa. Respir. Res. 6:26.1-26.16(2005) PubMed=18978040; DOI=10.1152/ajplung.90314.2008; PMCID=PMC2636952 Marian Leslie Fulcher, Sherif E. Gabriel, John C. Olsen, Jason R. Tatreau, Martina Gentzsch, Elizabeth Livanos-Gonzalez, Mimi T. Saavedra, Patrick Salmon, Scott H. Randell; Novel human bronchial epithelial cell lines for cystic fibrosis research. Am. J. Physiol. Lung Cell. Mol. Physiol. 296:L82-L91(2009)
Encyclopedic resources	Wikidata; Q98125458
Entry history
Entry creation	02-Jul-2020
Last entry update	14-Aug-2025
Version number	11