ID   AALEB
AC   CVCL_ZC94
DR   Wikidata; Q98125458
RX   PubMed=12085236;
RX   PubMed=15804356;
RX   PubMed=18978040;
WW   Provider; UNC OTC; 19-0116; https://web.archive.org/web/20200120011157/http://technologies.unc.edu/technologies/19-0116_cell-line-aaleb
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Lung, bronchus, tracheobronchial epithelium; UBERON=UBERON_0008397.
CC   Cell type: Epithelial cell of tracheobronchial tree; CL=CL_0002202.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 02-07-20; Last updated: 10-04-25; Version: 10
//
RX   PubMed=12085236; DOI=10.1038/sj.onc.1205550;
RA   Lundberg A.S., Randell S.H., Stewart S.A., Elenbaas B., Hartwell K.A.,
RA   Brooks M.W., Fleming M.D., Olsen J.C., Miller S.W., Weinberg R.A.,
RA   Hahn W.C.;
RT   "Immortalization and transformation of primary human airway epithelial
RT   cells by gene transfer.";
RL   Oncogene 21:4577-4586(2002).
//
RX   PubMed=15804356; DOI=10.1186/1465-9921-6-26; PMCID=PMC1087506;
RA   Wu Q., Lu Z., Verghese M.W., Randell S.H.;
RT   "Airway epithelial cell tolerance to Pseudomonas aeruginosa.";
RL   Respir. Res. 6:26.1-26.16(2005).
//
RX   PubMed=18978040; DOI=10.1152/ajplung.90314.2008; PMCID=PMC2636952;
RA   Fulcher M.L., Gabriel S.E., Olsen J.C., Tatreau J.R., Gentzsch M.,
RA   Livanos-Gonzalez E., Saavedra M.T., Salmon P., Randell S.H.;
RT   "Novel human bronchial epithelial cell lines for cystic fibrosis
RT   research.";
RL   Am. J. Physiol. Lung Cell. Mol. Physiol. 296:L82-L91(2009).
//