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Cellosaurus PC-3 ML-Luc (CVCL_ZC63)

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Cell line name PC-3 ML-Luc
Synonyms PC-3-ML-Luciferase
Accession CVCL_ZC63
Resource Identification Initiative To cite this cell line use: PC-3 ML-Luc (RRID:CVCL_ZC63)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6E90 (PC-3 ML)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=22275356; DOI=10.1074/jbc.M111.302547; PMCID=PMC3322861
Thomas P. Lynch, Christina M. Ferrer, S. RaElle Jackson, Kristina S. Shahriari, Keith Vosseller, Mauricio J. Reginato;
Critical role of O-linked beta-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis.
J. Biol. Chem. 287:11070-11081(2012)

Cross-references
Cell line collections (Providers) Kerafast; EDX002 - Discontinued
Cell line databases/resources cancercelllines; CVCL_ZC63
Encyclopedic resources Wikidata; Q98128500
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number12