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Cellosaurus MKN45R0.08 (CVCL_Z942)

[Text version]
Cell line name MKN45R0.08
Accession CVCL_Z942
Resource Identification Initiative To cite this cell line use: MKN45R0.08 (RRID:CVCL_Z942)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

CLPUB00210
Kyo Ueki, Kikuo Aizawa, Shinsuke Tanaka, Tadashi Nishimaki, Tsutomu Suzuki;
Characterization of low- and high-level adriamycin-resistant human gastric cancer cell lines: flow cytometric studies and reversal effect of verapamil.
Acta Med. Biol. 47:161-167(1999)

Cross-references
Cell line databases/resources cancercelllines; CVCL_Z942
Encyclopedic resources Wikidata; Q54905830
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number14