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Cellosaurus MKN45R0.05 (CVCL_Z941)

[Text version]
Cell line name MKN45R0.05
Accession CVCL_Z941
Resource Identification Initiative To cite this cell line use: MKN45R0.05 (RRID:CVCL_Z941)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line

Ueki K., Aizawa K., Tanaka S., Nishimaki T., Suzuki T.
Characterization of low- and high-level adriamycin-resistant human gastric cancer cell lines: flow cytometric studies and reversal effect of verapamil.
Acta Med. Biol. 47:161-167(1999)

Cell line databases/resources cancercelllines; CVCL_Z941
Encyclopedic resources Wikidata; Q54905829
Entry history
Entry creation10-Apr-2015
Last entry update05-Oct-2023
Version number13