Cellosaurus logo
expasy logo

Cellosaurus RML-12 (CVCL_Z829)

[Text version]
Cell line name RML-12
Synonyms RML12; Rocky Mountain Laboratory-12
Accession CVCL_Z829
Resource Identification Initiative To cite this cell line use: RML-12 (RRID:CVCL_Z829)
Comments Group: Insect cell line.
Problematic cell line: Misidentified. Originally thought to be of Aedes aegypti origin but found to be from Aedes albopictus (PubMed=19951376).
Species of origin Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta) (NCBI Taxonomy: 7160)
Hierarchy Children:
CVCL_ZF40 (RML12.wMelPopCLA)
Sex of cell Sex unspecified
Age at sampling Larval stage
Category Spontaneously immortalized cell line
Publications

DOI=10.1016/B978-0-12-470270-7.50022-7
Walter Frederic Hink;
A compilation of invertebrate cell lines and culture media.
(In book chapter) Invertebrate tissue culture: research applications; Maramorosch, Karl (eds.); pp.319-369; Academic Press; New York; USA (1976)

PubMed=6137452; DOI=10.1007/BF02628962
Goro Kuno;
Cultivation of mosquito cell lines in serum-free media and their effects on dengue virus replication.
In Vitro 19:707-713(1983)

PubMed=2563994; DOI=10.1007/BF02626177
Goro Kuno, Antonio Oliver;
Maintaining mosquito cell lines at high temperatures: effects on the replication of flaviviruses.
In Vitro Cell. Dev. Biol. 25:193-196(1989)

PubMed=18836024; DOI=10.1128/AEM.01038-08; PMCID=PMC2583474
Conor J. McMeniman, Amanda M. Lane, Amy W.C. Fong, Denis A. Voronin, Inaki Iturbe-Ormaetxe, Ryuichi Yamada, Elizabeth Ann McGraw, Scott L. O'Neill;
Host adaptation of a Wolbachia strain after long-term serial passage in mosquito cell lines.
Appl. Environ. Microbiol. 74:6963-6969(2008)

PubMed=19951376; DOI=10.1111/j.1365-2672.2009.04621.x
Denis A. Voronin, Van Tran-Van, Patrick Potier, Patrick Mavingui;
Transinfection and growth discrepancy of Drosophila Wolbachia strain wMel in cell lines of the mosquito Aedes albopictus.
J. Appl. Microbiol. 108:2133-2141(2010)

PubMed=20976219; DOI=10.1371/journal.pone.0013398; PMCID=PMC2955527
Francesca D. Frentiu, Jodie Robinson, Paul R. Young, Elizabeth Ann McGraw, Scott L. O'Neill;
Wolbachia-mediated resistance to dengue virus infection and death at the cellular level.
PLoS ONE 5:e13398.1-e13398.8(2010)

PubMed=26519596; DOI=10.1016/j.virol.2015.07.021
Breeanna Jessica McLean, Jody Hobson-Peters, Cameron E. Webb, Daniel Watterson, Natalie A. Prow, Hong Duyen Nguyen, Sonja Hall-Mendelin, David Warrilow, Cheryl A. Johansen, Cassie C. Jansen, Andrew F. van den Hurk ...Show all 15 authors... , Nigel W. Beebe, Esther Schnettler, Ross T. Barnard, Roy A. Hall; Show fewer authors
A novel insect-specific flavivirus replicates only in Aedes-derived cells and persists at high prevalence in wild Aedes vigilax populations in Sydney, Australia.
Virology 486:272-283(2015)

PubMed=29973702; DOI=10.1038/s41598-018-28357-2; PMCID=PMC6031678
Julie Gaburro, Jean-Bernard Duchemin, Prasad N. Paradkar, Saeid Nahavandi, Asim Bhatti;
Electrophysiological evidence of RML12 mosquito cell line towards neuronal differentiation by 20-hydroxyecdysdone.
Sci. Rep. 8:10109-10109(2018)

Cross-references
Encyclopedic resources Wikidata; Q54950676
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number9