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Cellosaurus RML-12 (CVCL_Z829)

[Text version]
Cell line name RML-12
Synonyms RML12
Accession CVCL_Z829
Resource Identification Initiative To cite this cell line use: RML-12 (RRID:CVCL_Z829)
Comments Group: Insect cell line.
Problematic cell line: Misidentified. Originally thought to be of Aedes aegypti origin but found to be from Aedes albopictus (PubMed=19951376; PubMed=29973702).
Species of origin Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta) (NCBI Taxonomy: 7160)
Hierarchy Children:
CVCL_ZF40 (RML12.wMelPopCLA)
Sex of cell Sex unspecified
Age at sampling Larval stage
Category Spontaneously immortalized cell line

PubMed=6137452; DOI=10.1007/BF02628962
Kuno G.
Cultivation of mosquito cell lines in serum-free media and their effects on dengue virus replication.
In Vitro 19:707-713(1983)

PubMed=2563994; DOI=10.1007/BF02626177
Kuno G., Oliver A.
Maintaining mosquito cell lines at high temperatures: effects on the replication of flaviviruses.
In Vitro Cell. Dev. Biol. 25:193-196(1989)

PubMed=18836024; DOI=10.1128/AEM.01038-08
McMeniman C.J., Lane A.M., Fong A.W.C., Voronin D.A., Iturbe-Ormaetxe I., Yamada R., McGraw E.A., O'Neill S.L.
Host adaptation of a Wolbachia strain after long-term serial passage in mosquito cell lines.
Appl. Environ. Microbiol. 74:6963-6969(2008)

PubMed=19951376; DOI=10.1111/j.1365-2672.2009.04621.x
Voronin D.A., Tran-Van V., Potier P., Mavingui P.
Transinfection and growth discrepancy of Drosophila Wolbachia strain wMel in cell lines of the mosquito Aedes albopictus.
J. Appl. Microbiol. 108:2133-2141(2010)

PubMed=20976219; DOI=10.1371/journal.pone.0013398
Frentiu F.D., Robinson J., Young P.R., McGraw E.A., O'Neill S.L.
Wolbachia-mediated resistance to dengue virus infection and death at the cellular level.
PLoS ONE 5:E13398-E13398(2010)

PubMed=26519596; DOI=10.1016/j.virol.2015.07.021
McLean B.J., Hobson-Peters J., Webb C.E., Watterson D., Prow N.A., Nguyen H.D., Hall-Mendelin S., Warrilow D., Johansen C.A., Jansen C.C., van den Hurk A.F., Beebe N.W., Schnettler E., Barnard R.T., Hall R.A.
A novel insect-specific flavivirus replicates only in Aedes-derived cells and persists at high prevalence in wild Aedes vigilax populations in Sydney, Australia.
Virology 486:272-283(2015)

PubMed=29973702; DOI=10.1038/s41598-018-28357-2
Gaburro J., Duchemin J.-B., Paradkar P.N., Nahavandi S., Bhatti A.
Electrophysiological evidence of RML12 mosquito cell line towards neuronal differentiation by 20-hydroxyecdysdone.
Sci. Rep. 8:10109-10109(2018)

Encyclopedic resources Wikidata; Q54950676
Entry history
Entry creation10-Apr-2015
Last entry update21-Mar-2023
Version number8