Cellosaurus logo
expasy logo

Cellosaurus BM-N (CVCL_Z633)

[Text version]
Cell line name BM-N
Synonyms Bm N; BmN; BMN; BmN(1)
Accession CVCL_Z633
Resource Identification Initiative To cite this cell line use: BM-N (RRID:CVCL_Z633)
Comments Group: Insect cell line.
Group: Recombinant protein production insect cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8910.
Biotechnology: Used for the production of the VirBac Virbagen Omega, a recombinant cat alpha-inteferon used in veterinary medicine to treat cats infected with feline leukemia virus (FeLV) and/or feline immunodeficiency virus (FIV) infections.
Virology: Infected by Bombyx mori macula-like latent virus (BmMLV).
Omics: Deep proteome analysis.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Bombyx mori (Silk moth) (NCBI Taxonomy: 7091)
Hierarchy Children:
CVCL_Z634 (BmN4)
Sex of cell Female
Category Spontaneously immortalized cell line
Web pages https://www.ema.europa.eu/en/documents/scientific-discussion/virbagen-omega-epar-scientific-discussion_en.pdf

PubMed=16346059; DOI=10.1128/AEM.44.1.227-233.1982
Volkman L.E., Goldsmith P.A.
Generalized immunoassay for Autographa californica nuclear polyhedrosis virus infectivity in vitro.
Appl. Environ. Microbiol. 44:227-233(1982)

Maeda S.
A plaque assay and cloning of Bombyx mori nuclear polyhedrosis virus.
J. Seric. Sci. Jpn. 53:547-548(1984)

PubMed=2989694; DOI=10.1038/315592a0
Maeda S., Kawai T., Obinata M., Fujiwara H., Horiuchi T., Saeki Y., Sato Y., Furusawa M.
Production of human alpha-interferon in silkworm using a baculovirus vector.
Nature 315:592-594(1985)

Ninaki O., Takada N., Fujiwara H., Ogura T., Miyajima N., Kiyota A., Maekawa H.
Gene analysis by blot hybridization on the silkworm, Bombyx mori, cell lines.
(In) Invertebrate cell system applications, Vol. I; Mitsuhashi J. (eds.); pp.143-149; CRC Press; Boca Raton (1989)

PubMed=8799737; DOI=10.1111/j.1365-2583.1996.tb00053.x
McIntosh A.H., Grasela J.J., Matteri R.L.
Identification of insect cell lines by DNA amplification fingerprinting (DAF).
Insect Mol. Biol. 5:187-195(1996)

PubMed=10777062; DOI=10.1290/1071-2690(2000)036<0205:EOTGFP>2.0.CO;2
Grasela J.J., McIntosh A.H., Goodman C.L., Wilson L.E., King L.A.
Expression of the green fluorescent protein carried by Autographa californica multiple nucleopolyhedrovirus in insect cell lines.
In Vitro Cell. Dev. Biol. Anim. 36:205-210(2000)

PubMed=16409117; DOI=10.1290/0412083R.1
McIntosh A.H., Grasela J.J., Popham H.J.R.
AcMNPV in permissive, semipermissive, and nonpermissive cell lines from Arthropoda.
In Vitro Cell. Dev. Biol. Anim. 41:298-304(2005)

PubMed=19496755; DOI=10.1042/BSR20090045
Yao H.-P., Chen L., Xiang X.-W., Guo A.-Q., Lu X.-M., Wu X.-F.
Proteomics identification and annotation of proteins of a cell line of Bombyx mori, BmN cells.
Biosci. Rep. 30:209-215(2010)

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002
Geisler C., Jarvis D.L.
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2017)

Cell line collections (Providers) ATCC; CRL-8910
RCB; RCB0457
Cell line databases/resources CLO; CLO_0002008
CLO; CLO_0051457
CLDB; cl467
ICLDB; bmn
Anatomy/cell type resources BTO; BTO:0001267
Encyclopedic resources Wikidata; Q54797447
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number17