AC   CVCL_Z633
SY   Bm N; BmN; BMN; BmN(1)
DR   BTO; BTO:0001267
DR   CLO; CLO_0002008
DR   CLO; CLO_0051457
DR   CLDB; cl467
DR   ATCC; CRL-8910
DR   ICLDB; bmn
DR   NISES; SK0010
DR   RCB; RCB0457
DR   Wikidata; Q54797447
RX   CelloPub=CLPUB00498;
RX   DOI=10.11416/kontyushigen1930.53.547;
RX   PubMed=2989694;
RX   PubMed=8799737;
RX   PubMed=10777062;
RX   PubMed=16346059;
RX   PubMed=16409117;
RX   PubMed=19496755;
RX   PubMed=29133148;
CC   Group: Insect cell line.
CC   Group: Recombinant protein production insect cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8910.
CC   Biotechnology: Used for the production of the VirBac Virbagen Omega, a recombinant cat alpha-inteferon used in veterinary medicine to treat cats infected with feline leukemia virus (FeLV) and/or feline immunodeficiency virus (FIV) infections.
CC   Virology: Infected by Bombyx mori macula-like latent virus (BmMLV).
CC   Omics: Deep proteome analysis.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
OX   NCBI_TaxID=7091; ! Bombyx mori (Silk moth)
SX   Female
CA   Spontaneously immortalized cell line
DT   Created: 10-04-15; Last updated: 29-06-23; Version: 17
RX   CelloPub=CLPUB00498;
RA   Ninaki O., Takada N., Fujiwara H., Ogura T., Miyajima N., Kiyota A.,
RA   Maekawa H.;
RT   "Gene analysis by blot hybridization on the silkworm, Bombyx mori, cell
RT   lines.";
RL   (In) Invertebrate cell system applications, Vol. I; Mitsuhashi J. (eds.); pp.143-149; CRC Press; Boca Raton (1989).
RX   DOI=10.11416/kontyushigen1930.53.547;
RA   Maeda S.;
RT   "A plaque assay and cloning of Bombyx mori nuclear polyhedrosis
RT   virus.";
RL   J. Seric. Sci. Jpn. 53:547-548(1984).
RX   PubMed=2989694; DOI=10.1038/315592a0;
RA   Maeda S., Kawai T., Obinata M., Fujiwara H., Horiuchi T., Saeki Y.,
RA   Sato Y., Furusawa M.;
RT   "Production of human alpha-interferon in silkworm using a baculovirus
RT   vector.";
RL   Nature 315:592-594(1985).
RX   PubMed=8799737; DOI=10.1111/j.1365-2583.1996.tb00053.x;
RA   McIntosh A.H., Grasela J.J., Matteri R.L.;
RT   "Identification of insect cell lines by DNA amplification
RT   fingerprinting (DAF).";
RL   Insect Mol. Biol. 5:187-195(1996).
RX   PubMed=10777062; DOI=10.1290/1071-2690(2000)036<0205:EOTGFP>2.0.CO;2;
RA   Grasela J.J., McIntosh A.H., Goodman C.L., Wilson L.E., King L.A.;
RT   "Expression of the green fluorescent protein carried by Autographa
RT   californica multiple nucleopolyhedrovirus in insect cell lines.";
RL   In Vitro Cell. Dev. Biol. Anim. 36:205-210(2000).
RX   PubMed=16346059; DOI=10.1128/AEM.44.1.227-233.1982;
RA   Volkman L.E., Goldsmith P.A.;
RT   "Generalized immunoassay for Autographa californica nuclear
RT   polyhedrosis virus infectivity in vitro.";
RL   Appl. Environ. Microbiol. 44:227-233(1982).
RX   PubMed=16409117; DOI=10.1290/0412083R.1;
RA   McIntosh A.H., Grasela J.J., Popham H.J.R.;
RT   "AcMNPV in permissive, semipermissive, and nonpermissive cell lines
RT   from Arthropoda.";
RL   In Vitro Cell. Dev. Biol. Anim. 41:298-304(2005).
RX   PubMed=19496755; DOI=10.1042/BSR20090045;
RA   Yao H.-P., Chen L., Xiang X.-W., Guo A.-Q., Lu X.-M., Wu X.-F.;
RT   "Proteomics identification and annotation of proteins of a cell line
RT   of Bombyx mori, BmN cells.";
RL   Biosci. Rep. 30:209-215(2010).
RX   PubMed=29133148; DOI=10.1016/j.pep.2017.11.002;
RA   Geisler C., Jarvis D.L.;
RT   "Adventitious viruses in insect cell lines used for recombinant
RT   protein expression.";
RL   Protein Expr. Purif. 144:25-32(2017).