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Cellosaurus SK-astrocyte-IDH1 (CVCL_Z595)

[Text version]
Cell line name SK-astrocyte-IDH1
Accession CVCL_Z595
Resource Identification Initiative To cite this cell line use: SK-astrocyte-IDH1 (RRID:CVCL_Z595)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2012-113.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5382; IDH1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E3G4 (NHA E6/E7/hTERT/Ras)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=22343889; DOI=10.1038/nature10866; PMCID=PMC3351699
Sevin Turcan, Daniel Rohle, Anuj Goenka, Logan A. Walsh, Fang Fang, Emrullah Yilmaz, Carl Campos, Armida W.M. Fabius, Chao Lu, Patrick S. Ward, Craig B. Thompson ...Show all 20 authors... , Andrew Kaufman, Olga Guryanova, Ross Levine, Adriana Heguy, Agnes J. Viale, Luc G.T. Morris, Jason T. Huse, Ingo K. Mellinghoff, Timothy A. Chan; Show fewer authors
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
Nature 483:479-483(2012)

Cross-references
Encyclopedic resources Wikidata; Q54953609
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number11