Cellosaurus cell line HO-323 (CVCL

Cellosaurus HO-323 (CVCL_Z045)

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Cell line name

HO-323

Synonyms

HO 323/WIL2.NS; HO323

Accession

CVCL_Z045

Resource Identification Initiative

To cite this cell line use: HO-323 (RRID:CVCL_Z045)

Comments

Group: Hybridoma fusion partner cell line.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Cell type: B-cell; CL=CL_0000236.

Sequence variations

Mutation; HGNC; HGNC:11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>A); ClinVar=VCV000142714; Zygosity=Homozygous (from parent cell line).

Disease

Hereditary spherocytosis (NCIt: C97074)
Hereditary spherocytosis (ORDO: Orphanet_822)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_2761 (WIL2 NS)
Children:

CVCL_B6CT (9L-27-9)	CVCL_B6CU (9P-13-4)	CVCL_B6CK (EMK-F7)
CVCL_B6CL (FMK-H3)	CVCL_B6CI (HB-5)	CVCL_B6CG (HB-7)
CVCL_B6CE (HF-4)	CVCL_B6CF (HF-7)	CVCL_B6CH (HL-259)
CVCL_B6CC (HL-321)	CVCL_B6CD (HL-349)	CVCL_B6C9 (HO-323-3)
CVCL_B6CM (KMK-41)	CVCL_B6CN (SH-75)	CVCL_B6CP (SH-76)
CVCL_B6CQ (SH-77)	CVCL_B6CR (SH-78)	CVCL_B6CS (SH-83)
CVCL_B6CJ (SH-9 [Human hybridoma against poly(dT)])	CVCL_B6CB (SU-1)

Sex of cell

Male

Age at sampling