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Cellosaurus HO-323 (CVCL_Z045)

[Text version]
Cell line name HO-323
Synonyms HO 323/WIL2.NS; HO323
Accession CVCL_Z045
Resource Identification Initiative To cite this cell line use: HO-323 (RRID:CVCL_Z045)
Comments Group: Hybridoma fusion partner cell line.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Sequence variations
  • Mutation; HGNC; 11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>A); ClinVar=VCV000142714; Zygosity=Homozygous (from parent cell line).
Disease Hereditary spherocytosis (NCIt: C97074)
Hereditary spherocytosis (ORDO: Orphanet_822)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2761 (WIL2 NS)
CVCL_B6CT (9L-27-9)CVCL_B6CU (9P-13-4)CVCL_B6CK (EMK-F7)
CVCL_B6CC (HL-321)CVCL_B6CD (HL-349)CVCL_B6C9 (HO-323-3)
CVCL_B6CJ (SH-9 [Human hybridoma against poly(dT)])CVCL_B6CB (SU-1)
Sex of cell Male
Age at sampling 5Y
Category Transformed cell line

PubMed=3485476; DOI=10.1016/0309-1651(86)90090-1
Ohashi H., Hashizume S., Murakami H., Aihara K., Shinohara K., Omura H.
HO-323, a human B-lymphoblastoid cell line useful for making human-human hybridomas.
Cell Biol. Int. Rep. 10:77-83(1986)

Encyclopedic resources Wikidata; Q54890090
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number12