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Cellosaurus Vero.STAT1 KO (CVCL_YZ45)

[Text version]
Cell line name Vero.STAT1 KO
Synonyms Vero.STAT1-KO
Accession CVCL_YZ45
Resource Identification Initiative To cite this cell line use: Vero.STAT1 KO (RRID:CVCL_YZ45)
Comments Group: Non-human primate cell line.
Group: Vaccine production cell line.
Virology: Excellent cell model for virus propagation and viral vaccine production. It exhibits significant increased viral titer and enhanced virus production capability when compared to its parental cell line (ATCC=CCL-81-VHG).
Doubling time: ~28 hours (ATCC=CCL-81-VHG).
Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RIE1; STAT1.
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0059 (Vero)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

Turner-Gillies E., Shapiro B.A., Tian F.
Generation of cell lines capable of producing high-titer viral stocks for use in vaccine manufacture and gene therapy.
(In) ATCC application note AP-082021-v01; pp.1-8; ATCC; Manassas (2021)

Cell line collections (Providers) ATCC; CCL-81-VHG
Encyclopedic resources Wikidata; Q98134511
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number8