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Cellosaurus Vero.STAT1 KO (CVCL_YZ45)

[Text version]
Cell line name Vero.STAT1 KO
Synonyms Vero.STAT1-KO
Accession CVCL_YZ45
Resource Identification Initiative To cite this cell line use: Vero.STAT1 KO (RRID:CVCL_YZ45)
Comments Group: Non-human primate cell line.
Group: Vaccine production cell line.
Virology: Excellent cell model for virus propagation and viral vaccine production. It exhibits significant increased viral titer and enhanced virus production capability when compared to its parental cell line (ATCC).
Doubling time: ~28 hours (ATCC).
Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RIE1; STAT1.
Derived from sampling site: Kidney; epithelium.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0059 (Vero)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

Turner-Gillies E., Shapiro B.A., Tian F.
Generation of cell lines capable of producing high-titer viral stocks for use in vaccine manufacture and gene therapy.
(In) ATCC application note AP-082021-v01; pp.1-8; ATCC; Manassas (2021)

Cell line collections ATCC; CCL-81-VHG
Encyclopedic resources Wikidata; Q98134511
Entry history
Entry creation02-Jul-2020
Last entry update15-Dec-2022
Version number5