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Cellosaurus MKN45/CDDP/R1 (CVCL_YX96)

[Text version]
Cell line name MKN45/CDDP/R1
Accession CVCL_YX96
Resource Identification Initiative To cite this cell line use: MKN45/CDDP/R1 (RRID:CVCL_YX96)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line

Tozawa K., Oshima T., Kobayashi T., Yamamoto N., Hayashi C., Matsumoto T., Miwa H.
Oxaliplatin in treatment of the cisplatin-resistant MKN45 cell line of gastric cancer.
Anticancer Res. 28:2087-2092(2008)

Cell line databases/resources cancercelllines; CVCL_YX96
Encyclopedic resources Wikidata; Q95989944
Entry history
Entry creation12-Mar-2020
Last entry update05-Oct-2023
Version number7