Cellosaurus A20 NF-kappaB (CVCL_YU22)
| Cell line name | A20 NF-kappaB |
|---|---|
| Synonyms | A20_NF-kappaB |
| Accession | CVCL_YU22 |
| Resource Identification Initiative | To cite this cell line use: A20 NF-kappaB (RRID:CVCL_YU22) |
| Comments | Characteristics: Reporter cell line for the measurement of the biological activity of a wide variety of cytokines (PubMed=32094407). Characteristics: Activated by NF-kappaB through a NF-kappaB response element fused to a secNanoLuc-T2A-mCherry construct (PubMed=32094407). Genetic integration: Method=Transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)). Genetic integration: Method=Transduction; Gene=Oplophorus gracilirostris NanoLuc (Note=19 kDa ATP-independent bright luminescent protein derived from O.gracilirostris luciferase). Cell type: B-cell; CL=CL_0000236. |
| Disease | Mouse reticulum cell sarcoma (NCIt: C134780) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cAnN. |
| Hierarchy | Parent: CVCL_1940 (A20) |
| Sex of cell | Sex unspecified |
| Age at sampling | >15M |
| Category | Cancer cell line |
| Publications | PubMed=32094407; DOI=10.1038/s41598-020-60182-4; PMCID=PMC7040017 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q93311424 |
| Entry history | |
| Entry creation | 12-Mar-2020 |
| Last entry update | 14-Aug-2025 |
| Version number | 11 |