ID   A20 NF-kappaB
AC   CVCL_YU22
SY   A20_NF-kappaB
DR   Wikidata; Q93311424
RX   PubMed=32094407;
CC   Characteristics: Reporter cell line for the measurement of the biological activity of a wide variety of cytokines (PubMed=32094407).
CC   Characteristics: Activated by NF-kappaB through a NF-kappaB response element fused to a secNanoLuc-T2A-mCherry construct (PubMed=32094407).
CC   Genetic integration: Method=Transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
CC   Genetic integration: Method=Transduction; Gene=Oplophorus gracilirostris NanoLuc (Note=19 kDa ATP-independent bright luminescent protein derived from O.gracilirostris luciferase).
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: BALB/cAnN.
DI   NCIt; C134780; Mouse reticulum cell sarcoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_1940 ! A20
SX   Sex unspecified
AG   >15M
CA   Cancer cell line
DT   Created: 12-03-20; Last updated: 14-08-25; Version: 11
//
RX   PubMed=32094407; DOI=10.1038/s41598-020-60182-4; PMCID=PMC7040017;
RA   Mock, Jacqueline
RA   Pellegrino, Christian
RA   Neri, Dario
RT   "A universal reporter cell line for bioactivity evaluation of
RT   engineered cytokine products.";
RL   Sci. Rep. 10:3234.1-3234.10(2020).
//