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Cellosaurus VeroE6/TMPRSS2 (CVCL_YQ49)

[Text version]
Cell line name VeroE6/TMPRSS2
Accession CVCL_YQ49
Resource Identification Initiative To cite this cell line use: VeroE6/TMPRSS2 (RRID:CVCL_YQ49)
Comments Group: Non-human primate cell line.
Group: SARS-CoV-2 research cell line.
Virology: Highly susceptible to infection by Middle East respiratory syndrome-related coronavirus (MERS-CoV), SARS coronavirus (SARS-CoV) and SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=32165541).
Transfected with: HGNC; 11876; TMPRSS2.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0574 (Vero C1008)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://www.nibsc.org/products/brm_product_catalogue/detail_page.aspx?catid=100978

PubMed=31013314; DOI=10.1371/journal.pone.0215822
Nao N., Sato K., Yamagishi J., Tahara M., Nakatsu Y., Seki F., Katoh H., Ohnuma A., Shirogane Y., Hayashi M., Suzuki T., Kikuta H., Nishimura H., Takeda M.
Consensus and variations in cell line specificity among human metapneumovirus strains.
PLoS ONE 14:E0215822-E0215822(2019)

PubMed=32165541; DOI=10.1073/pnas.2002589117
Matsuyama S., Nao N., Shirato K., Kawase M., Saito S., Takayama I., Nagata N., Sekizuka T., Katoh H., Kato F., Sakata M., Tahara M., Kutsuna S., Ohmagari N., Kuroda M., Suzuki T., Kageyama T., Takeda M.
Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.
Proc. Natl. Acad. Sci. U.S.A. 117:7001-7003(2020)

Cell line collections (Providers) JCRB; JCRB1819
Encyclopedic resources Wikidata; Q91354600
Entry history
Entry creation12-Mar-2020
Last entry update05-Oct-2023
Version number8