ID   VeroE6/TMPRSS2
AC   CVCL_YQ49
DR   JCRB; JCRB1819
DR   Wikidata; Q91354600
RX   PubMed=31013314;
RX   PubMed=32165541;
WW   https://www.nibsc.org/products/brm_product_catalogue/detail_page.aspx?catid=100978
CC   Group: Non-human primate cell line.
CC   Group: SARS-CoV-2 research cell line.
CC   Virology: Highly susceptible to infection by Middle East respiratory syndrome-related coronavirus (MERS-CoV), SARS coronavirus (SARS-CoV) and SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=32165541).
CC   Transfected with: HGNC; 11876; TMPRSS2.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=60711; ! Chlorocebus sabaeus (Green monkey)
HI   CVCL_0574 ! Vero C1008
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 12-03-20; Last updated: 05-10-23; Version: 8
//
RX   PubMed=31013314; DOI=10.1371/journal.pone.0215822;
RA   Nao N., Sato K., Yamagishi J., Tahara M., Nakatsu Y., Seki F.,
RA   Katoh H., Ohnuma A., Shirogane Y., Hayashi M., Suzuki T., Kikuta H.,
RA   Nishimura H., Takeda M.;
RT   "Consensus and variations in cell line specificity among human
RT   metapneumovirus strains.";
RL   PLoS ONE 14:E0215822-E0215822(2019).
//
RX   PubMed=32165541; DOI=10.1073/pnas.2002589117;
RA   Matsuyama S., Nao N., Shirato K., Kawase M., Saito S., Takayama I.,
RA   Nagata N., Sekizuka T., Katoh H., Kato F., Sakata M., Tahara M.,
RA   Kutsuna S., Ohmagari N., Kuroda M., Suzuki T., Kageyama T.,
RA   Takeda M.;
RT   "Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 117:7001-7003(2020).
//