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Cellosaurus LEPI (CVCL_YP10)

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Cell line name LEPI
Synonyms LEPI-1
Accession CVCL_YP10
Resource Identification Initiative To cite this cell line use: LEPI (RRID:CVCL_YP10)
Comments Characteristics: Rapidly forms cobblestone morphology, clear microvilli and tight barrier in simple culture conditions (PubMed=31412689).
Doubling time: ~20 hours (PubMed=31412689).
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0145 (ARPE-19)
Sex of cell Male
Age at sampling 19Y
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=31412689

Markers:
AmelogeninX,Y
CSF1PO11
D2S133819
D3S135814,15
D5S81813
D7S8209,11
D8S117913
D13S31711,12
D16S5399,11
D18S5112,16
D19S43312,13
D21S1128,29
FGA23
Penta D11,13
Penta E7,11
TH016,9.3
TPOX9,11
vWA16,19

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Publications

PubMed=31412689; DOI=10.3390/pharmaceutics11080412; PMCID=PMC6722654
Laura Hellinen, Lea Pirskanen, Unni Tengvall-Unadike, Arto Urtti, Mika Reinisalo;
Retinal pigment epithelial cell line with fast differentiation and improved barrier properties.
Pharmaceutics 11:412.1-412.12(2019)

Cross-references
Encyclopedic resources Wikidata; Q95982069
Entry history
Entry creation12-Mar-2020
Last entry update29-Jun-2023
Version number6