Cellosaurus cell line LINTERNA LS 174 (CVCL

Cross-references
Cell line name	LINTERNA LS 174
Synonyms	LINTERNA-LS174
Accession	CVCL_YJ85
Resource Identification Initiative	To cite this cell line use: LINTERNA LS 174 (RRID:CVCL_YJ85)
Comments	Population: Caucasian. Genetic integration: Method=Transfection; Gene=FPbase; A315M; TurboGFP (Note=Green fluorescent protein from P.plumata). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations	Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1384 (LS174T)
Sex of cell	Female
Age at sampling	58Y
Category	Cancer cell line
Cell line collections (Providers)	Innoprot; P20124
Cell line databases/resources	cancercelllines; CVCL_YJ85
Encyclopedic resources	Wikidata; Q95982229
Entry history
Entry creation	19-Dec-2019
Last entry update	14-Aug-2025
Version number	12