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Cellosaurus SK-BR-3 shWDR12-4 (CVCL_YJ28)

[Text version]
Cell line name SK-BR-3 shWDR12-4
Synonyms SKBR-3 shWDR12-4
Accession CVCL_YJ28
Resource Identification Initiative To cite this cell line use: SK-BR-3 shWDR12-4 (RRID:CVCL_YJ28)
Comments Population: Caucasian.
Doubling time: 36-39 hours (CelloPub=CLPUB00550).
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:14098; WDR12.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1748; CDH1; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

CLPUB00550
Sophie Benhamron;
Validating WDR12 as a potential drug target in triple negative breast cancer.
Thesis MSc (2019); University of Toronto; Toronto; Canada

Cross-references
Cell line databases/resources cancercelllines; CVCL_YJ28
Encyclopedic resources Wikidata; Q98132643
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number9