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Cellosaurus PK15 PERV-inactivated clone 20 (CVCL_YE76)

[Text version]
Cell line name PK15 PERV-inactivated clone 20
Synonyms PK15 clone 20; PK15-20
Accession CVCL_YE76
Resource Identification Initiative To cite this cell line use: PK15 PERV-inactivated clone 20 (RRID:CVCL_YE76)
Comments Characteristics: Using CRISPR/Cas9 all 62 copies of the PERV pol gene were inactivated (PubMed=26456528).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Hampshire.
Hierarchy Parent: CVCL_2160 (PK-15)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=26456528; DOI=10.1126/science.aad1191
Yang L.-H., Guell M., Niu D., George H., Lesha E., Grishin D., Aach J., Shrock E., Xu W.-H., Poci J., Cortazio R., Wilkinson R.A., Fishman J.A., Church G.M.
Genome-wide inactivation of porcine endogenous retroviruses (PERVs).
Science 350:1101-1104(2015)

Encyclopedic resources Wikidata; Q98128601
Entry history
Entry creation19-Dec-2019
Last entry update29-Jun-2023
Version number4