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Cellosaurus MeWo LNI 6I (CVCL_Y663)

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Cell line name MeWo LNI 6I
Accession CVCL_Y663
Resource Identification Initiative To cite this cell line use: MeWo LNI 6I (RRID:CVCL_Y663)
Comments Population: Caucasian.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6877; MAPK3; Simple; p.Pro246Ser (c.736C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln317Ter (c.949C>T); ClinVar=VCV000450344; Zygosity=Unspecified (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0445 (MeWo)
Sex of cell Male
Age at sampling 78Y
Category Cancer cell line
Publications

PubMed=1383272; DOI=10.1172/JCI116007; PMCID=PMC443186
John Nip, Henry Shibata, David J. Loskutoff, David A. Cheresh, Pnina Brodt;
Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin.
J. Clin. Invest. 90:1406-1413(1992)

Cross-references
Cell line databases/resources cancercelllines; CVCL_Y663
Encyclopedic resources Wikidata; Q54905344
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number14