ID   MeWo LNI 6I
AC   CVCL_Y663
DR   cancercelllines; CVCL_Y663
DR   Wikidata; Q54905344
RX   PubMed=1383272;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6877; MAPK3; Simple; p.Pro246Ser (c.736C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gln317Ter (c.949C>T); ClinVar=VCV000450344; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0445 ! MeWo
SX   Male
AG   78Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 30-01-24; Version: 12
//
RX   PubMed=1383272; DOI=10.1172/JCI116007;
RA   Nip J., Shibata H., Loskutoff D.J., Cheresh D.A., Brodt P.;
RT   "Human melanoma cells derived from lymphatic metastases use integrin
RT   alpha v beta 3 to adhere to lymph node vitronectin.";
RL   J. Clin. Invest. 90:1406-1413(1992).
//