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Cellosaurus CHO-AS52 (CVCL_Y504)

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Cell line name CHO-AS52
Synonyms CHO AS52; AS52
Accession CVCL_Y504
Resource Identification Initiative To cite this cell line use: CHO-AS52 (RRID:CVCL_Y504)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_Y503 (CHO-X3/5)
Children:
CVCL_RM50 (CHO-AS52 Ogg1(-/-)-Mutyh(-/-))
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-152.html
Publications

PubMed=6095070; DOI=10.1128/mcb.4.7.1411-1415.1984; PMCID=PMC368924
Kenneth R. Tindall, Leon F. Stankowski Jr., Richard Machanoff, Abraham W. Hsie;
Detection of deletion mutations in pSV2gpt-transformed cells.
Mol. Cell. Biol. 4:1411-1415(1984)

PubMed=2432598; DOI=10.1073/pnas.83.24.9616; PMCID=PMC387191
Abraham W. Hsie, Leslie Recio, D. Sue Katz, Cathy Q. Lee, Maria Wagner, Robert Lemoine Schenley;
Evidence for reactive oxygen species inducing mutations in mammalian cells.
Proc. Natl. Acad. Sci. U.S.A. 83:9616-9620(1986)

PubMed=3005850; DOI=10.1016/0027-5107(86)90036-9
Kenneth R. Tindall, Leon F. Stankowski Jr., Richard Machanoff, Abraham W. Hsie;
Analyses of mutation in pSV2gpt-transformed CHO cells.
Mutat. Res. 160:121-131(1986)

PubMed=29289706; DOI=10.1016/j.freeradbiomed.2017.12.035; PMCID=PMC5902796
Preechaya Tajai, Bogdan I. Fedeles, Tawit Suriyo, Panida Navasumrit, Jantamas Kanitwithayanun, John M. Essigmann, Jutamaad Satayavivad;
An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity.
Free Radic. Biol. Med. 116:64-72(2018)

Cross-references
Encyclopedic resources Wikidata; Q54812638
Entry history
Entry creation07-Nov-2014
Last entry update10-Apr-2025
Version number14