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Cellosaurus MKN45P (CVCL_Y476)

[Text version]
Cell line name MKN45P
Synonyms MKN-45P
Accession CVCL_Y476
Resource Identification Initiative To cite this cell line use: MKN45P (RRID:CVCL_Y476)
Comments Population: Japanese.
Characteristics: High-potential peritoneal dissemination child line of MKN45.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line

PubMed=17380436; DOI=10.1007/s10147-006-0616-z
Miyagi M., Aoyagi K., Kato S., Shirouzu K.
The TIMP-1 gene transferred through adenovirus mediation shows a suppressive effect on peritoneal metastases from gastric cancer.
Int. J. Clin. Oncol. 12:17-24(2007)

PubMed=22531121; DOI=10.2739/kurumemedj.58.73
Koga A., Aoyagi K., Imaizumi T., Miyagi M., Shirouzu K.
Comparison between the gastric cancer cell line MKN-45 and the high-potential peritoneal dissemination gastric cancer cell line MKN-45P.
Kurume Med. J. 58:73-79(2011)

Cell line databases/resources cancercelllines; CVCL_Y476
Encyclopedic resources Wikidata; Q54905828
Entry history
Entry creation07-Nov-2014
Last entry update05-Oct-2023
Version number13