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Cellosaurus L1210:RD1694 (CVCL_Y424)

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Cell line name L1210:RD1694
Synonyms L1210 (RD1694); L1210(RD1694)
Accession CVCL_Y424
Resource Identification Initiative To cite this cell line use: L1210:RD1694 (RRID:CVCL_Y424)
Comments Selected for resistance to: ChEBI; CHEBI_5847; ICI D1694 (Tomudex; ZD1694).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=7537518; DOI=10.1038/bjc.1995.178; PMCID=PMC2033796
Ann L. Jackman, Lloyd R. Kelland, Rosemary Kimbell, Margaret Brown, William Gibson, G. Wynne Aherne, Anthea Hardcastle, Francis Thomas Boyle;
Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.
Br. J. Cancer 71:914-924(1995)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307418
ChEMBL-Targets; CHEMBL614713
PubChem_Cell_line; CVCL_Y424
Encyclopedic resources Wikidata; Q54900970
Entry history
Entry creation07-Nov-2014
Last entry update19-Dec-2024
Version number14