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Cellosaurus L1210:RD1694 (CVCL_Y424)

[Text version]

Cell line name L1210:RD1694
Synonyms L1210 (RD1694); L1210(RD1694)
Accession CVCL_Y424
Resource Identification Initiative To cite this cell line use: L1210:RD1694 (RRID:CVCL_Y424)
Comments Selected for resistance to: ChEBI; CHEBI:5847; ICI D1694 (Tomudex; ZD1694).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from sampling site: Ascites.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line

PubMed=7537518; DOI=10.1038/bjc.1995.178
Jackman A.L., Kelland L.R., Kimbell R., Brown M., Gibson W., Aherne G.W., Hardcastle A., Boyle F.T.
Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.
Br. J. Cancer 71:914-924(1995)

Chemistry resources ChEMBL-Cells; CHEMBL3307418
ChEMBL-Targets; CHEMBL614713
Encyclopedic resources Wikidata; Q54900970
Entry history
Entry creation07-Nov-2014
Last entry update02-Jul-2020
Version number9