Home  |  Contact

Cellosaurus L1210/DDP2 (CVCL_Y421)

[Text version]

Cell line name L1210/DDP2
Accession CVCL_Y421
Resource Identification Initiative To cite this cell line use: L1210/DDP2 (RRID:CVCL_Y421)
Comments Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from sampling site: Ascites.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line

PubMed=3167012; DOI=10.1021/bi00413a022
Eastman A., Schulte N.
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
Biochemistry 27:4730-4734(1988)

PubMed=10200488; DOI=10.1038/sj.cdd.4400357
Segal-Bendirdjian E., Mannone L., Jacquemin-Sablon A.
Alteration in p53 pathway and defect in apoptosis contribute independently to cisplatin-resistance.
Cell Death Differ. 5:390-400(1998)

Encyclopedic resources Wikidata; Q54900961
Entry history
Entry creation07-Nov-2014
Last entry update02-Jul-2020
Version number8