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Cellosaurus H273 (CVCL_Y296)

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Cell line name H273
Accession CVCL_Y296
Resource Identification Initiative To cite this cell line use: H273 (RRID:CVCL_Y296)
Comments Population: Caucasian.
Karyotypic information: Has lost chromosome Y (from parent cell line).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11998; TP53 (Note=With p.Arg273His).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0060 (NCI-H1299)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=19382257; DOI=10.1002/jmv.21486
A.M.A. Nasirudeen, Ding-Xiang Liu;
Gene expression profiling by microarray analysis reveals an important role for caspase-1 in dengue virus-induced p53-mediated apoptosis.
J. Med. Virol. 81:1069-1081(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_Y296
Anatomy/cell type resources BTO; BTO_0005140
Encyclopedic resources Wikidata; Q54872038
Entry history
Entry creation07-Nov-2014
Last entry update19-Dec-2024
Version number15