Cellosaurus A-375 Human EGFR vIII (CVCL_XZ66)
Cell line name | A-375 Human EGFR vIII |
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Synonyms | A375-EGFRVIII; U87MG Human EGFR vIII |
Accession | CVCL_XZ66 |
Resource Identification Initiative | To cite this cell line use: A-375 Human EGFR vIII (RRID:CVCL_XZ66) |
Comments | Problematic cell line: Misidentified. Was originally thought to originate from the U87MG cell line. STR profiling carried out at KYinno has shown it was derived from A-375. Be aware of this issue if you obtained this cell line before it was indicated as being derived from K-562. Population: Caucasian. Doubling time: ~30 hours (KYinno=KC-1308). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val30_Arg297del = EGFRvIII). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511. |
Sequence variations |
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Disease | Amelanotic melanoma (NCIt: C3802) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0132 (A-375) |
Sex of cell | Female |
Age at sampling | 54Y |
Category | Cancer cell line |
Cross-references | |
Cell line collections (Providers) | KYinno; KC-1308 |
Cell line databases/resources | cancercelllines; CVCL_XZ66 |
Encyclopedic resources | Wikidata; Q98133791 |
Entry history | |
Entry creation | 19-Dec-2019 |
Last entry update | 14-Aug-2025 |
Version number | 11 |