Cellosaurus cell line NCI-N87 human CLDN18.2 (CVCL

Cross-references
Cell line name	NCI-N87 human CLDN18.2
Synonyms	NCI-N87-CLDN18.2
Accession	CVCL_XZ59
Resource Identification Initiative	To cite this cell line use: NCI-N87 human CLDN18.2 (RRID:CVCL_XZ59)
Comments	Doubling time: ~30 hours (KYinno=KC-1222). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2039; CLDN18 (Note=Isoform A2). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations	Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:3431; ERBB3; Simple; p.Thr757Lys (c.2270C>A); Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease	Gastric tubular adenocarcinoma (NCIt: C5473)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1603 (NCI-N87)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Cell line collections (Providers)	KYinno; KC-1222
Cell line databases/resources	cancercelllines; CVCL_XZ59
Encyclopedic resources	Wikidata; Q95993869
Entry history
Entry creation	19-Dec-2019
Last entry update	14-Aug-2025
Version number	11