Cellosaurus cell line HT1080 human CD27 (CVCL

Cross-references
Cell line name	HT1080 human CD27
Synonyms	HT1080-CD27
Accession	CVCL_XZ55
Resource Identification Initiative	To cite this cell line use: HT1080 human CD27 (RRID:CVCL_XZ55)
Comments	Population: Caucasian. Doubling time: ~48 hours (KYinno=KC-0144). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11922; CD27. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease	Fibrosarcoma (NCIt: C3043) Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0317 (HT-1080)
Sex of cell	Male
Age at sampling	35Y
Category	Cancer cell line
Cell line collections (Providers)	KYinno; KC-0144 - Discontinued
Cell line databases/resources	cancercelllines; CVCL_XZ55
Encyclopedic resources	Wikidata; Q94094830
Entry history
Entry creation	19-Dec-2019
Last entry update	14-Aug-2025
Version number	13