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Cellosaurus HepG2-CAR (CVCL_XI50)

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Cell line name HepG2-CAR
Accession CVCL_XI50
Resource Identification Initiative To cite this cell line use: HepG2-CAR (RRID:CVCL_XI50)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7969; NR1I3.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

Patent=US20190256822
Vincent A. van der Mark;
Hepatic cell line resistant to dimethyl sulfoxide, cell culture and uses thereof.
Patent number US20190256822, 22-Aug-2019

Cross-references
Cell line databases/resources cancercelllines; CVCL_XI50
Encyclopedic resources Wikidata; Q94103341
Entry history
Entry creation19-Dec-2019
Last entry update14-Aug-2025
Version number12