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Cellosaurus HT-1080 JH-1/FIX (CVCL_XG90)

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Cell line name HT-1080 JH-1/FIX
Synonyms JH-1 / FIX
Accession CVCL_XG90
Resource Identification Initiative To cite this cell line use: HT-1080 JH-1/FIX (RRID:CVCL_XG90)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C200005.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3551; F9.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Publications

Patent=US7361639
Jia-Hui Xia;
Gene therapy agent for haemophilia B and its preparation method.
Patent number US7361639, 22-Apr-2008

Cross-references
Cell line databases/resources cancercelllines; CVCL_XG90
Encyclopedic resources Wikidata; Q94304215
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number14