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Cellosaurus 58As1 (CVCL_XG63)

[Text version]
Cell line name 58As1
Accession CVCL_XG63
Resource Identification Initiative To cite this cell line use: 58As1 (RRID:CVCL_XG63)
Comments Population: Japanese.
Characteristics: Highly metastatic. Strong capability of inducing the formation of ascites.
Characteristics: Parent cell line was injected subcutaneously into BALB/c nude mice. Cells from metastatic ascitic tumor cells were harvested and re-injected into mice. This process was carried out 12 times.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A391 (HSC-58)
Children:
CVCL_A9K1 (58As1mLuc)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=15958054; DOI=10.1111/j.1349-7006.2005.00054.x
Yanagihara K., Takigahira M., Tanaka H., Komatsu T., Fukumoto H., Koizumi F., Nishio K., Ochiya T., Ino Y., Hirohashi S.
Development and biological analysis of peritoneal metastasis mouse models for human scirrhous stomach cancer.
Cancer Sci. 96:323-332(2005)

PubMed=19010905; DOI=10.1158/0008-5472.CAN-08-2822
Nakajima T.E., Yanagihara K., Takigahira M., Yasunaga M., Kato K., Hamaguchi T., Yamada Y., Shimada Y., Mihara K., Ochiya T., Matsumura Y.
Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.
Cancer Res. 68:9318-9322(2008)

PubMed=22844455; DOI=10.1371/journal.pone.0041312
Ureshino H., Murakami Y., Watari K., Izumi H., Kawahara A., Kage M., Arao T., Nishio K., Yanagihara K., Kinoshita H., Kuwano M., Ono M.
N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition.
PLoS ONE 7:E41312-E41312(2012)

PubMed=26934957; DOI=10.1038/srep22371
Kurashige J., Hasegawa T., Niida A., Sugimachi K., Deng N., Mima K., Uchi R., Sawada G., Takahashi Y., Eguchi H., Inomata M., Kitano S., Fukagawa T., Sasako M., Sasaki H., Sasaki S., Mori M., Yanagihara K., Baba H., Miyano S., Tan P., Mimori K.
Integrated molecular profiling of human gastric cancer identifies DDR2 as a potential regulator of peritoneal dissemination.
Sci. Rep. 6:22371-22371(2016)

Cross-references
Encyclopedic resources Wikidata; Q93307924
Entry history
Entry creation06-Sep-2019
Last entry update29-Jun-2023
Version number5