ID   58As1
AC   CVCL_XG63
DR   Wikidata; Q93307924
RX   PubMed=15958054;
RX   PubMed=19010905;
RX   PubMed=22844455;
RX   PubMed=26934957;
CC   Population: Japanese.
CC   Characteristics: Highly metastatic. Strong capability of inducing the formation of ascites.
CC   Characteristics: Parent cell line was injected subcutaneously into BALB/c nude mice. Cells from metastatic ascitic tumor cells were harvested and re-injected into mice. This process was carried out 12 times.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C5250; Gastric signet ring cell adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A391 ! HSC-58
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 29-06-23; Version: 5
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RX   PubMed=15958054; DOI=10.1111/j.1349-7006.2005.00054.x; PMCID=PMC11158165;
RA   Yanagihara K., Takigahira M., Tanaka H., Komatsu T., Fukumoto H.,
RA   Koizumi F., Nishio K., Ochiya T., Ino Y., Hirohashi S.;
RT   "Development and biological analysis of peritoneal metastasis mouse
RT   models for human scirrhous stomach cancer.";
RL   Cancer Sci. 96:323-332(2005).
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RX   PubMed=19010905; DOI=10.1158/0008-5472.CAN-08-2822;
RA   Nakajima T.E., Yanagihara K., Takigahira M., Yasunaga M., Kato K.,
RA   Hamaguchi T., Yamada Y., Shimada Y., Mihara K., Ochiya T.,
RA   Matsumura Y.;
RT   "Antitumor effect of SN-38-releasing polymeric micelles, NK012, on
RT   spontaneous peritoneal metastases from orthotopic gastric cancer in
RT   mice compared with irinotecan.";
RL   Cancer Res. 68:9318-9322(2008).
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RX   PubMed=22844455; DOI=10.1371/journal.pone.0041312; PMCID=PMC3402489;
RA   Ureshino H., Murakami Y., Watari K., Izumi H., Kawahara A., Kage M.,
RA   Arao T., Nishio K., Yanagihara K., Kinoshita H., Kuwano M., Ono M.;
RT   "N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of
RT   human scirrhous gastric cancer cells through epithelial mesenchymal
RT   transition.";
RL   PLoS ONE 7:e41312.1-e41312.13(2012).
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RX   PubMed=26934957; DOI=10.1038/srep22371; PMCID=PMC4776110;
RA   Kurashige J., Hasegawa T., Niida A., Sugimachi K., Deng N., Mima K.,
RA   Uchi R., Sawada G., Takahashi Y., Eguchi H., Inomata M., Kitano S.,
RA   Fukagawa T., Sasako M., Sasaki H., Sasaki S., Mori M., Yanagihara K.,
RA   Baba H., Miyano S., Tan P., Mimori K.;
RT   "Integrated molecular profiling of human gastric cancer identifies
RT   DDR2 as a potential regulator of peritoneal dissemination.";
RL   Sci. Rep. 6:22371-22371(2016).
//