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Cellosaurus HiB5 (CVCL_XF91)

[Text version]
Cell line name HiB5
Accession CVCL_XF91
Resource Identification Initiative To cite this cell line use: HiB5 (RRID:CVCL_XF91)
Comments Characteristics: Proliferates at the permissive temperature (33 Celsius). Differentiates at the restrictive temperature (37 Celsius).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic brain, hippocampus; UBERON=UBERON_0006238+UBERON_0002421.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Hierarchy Children:
CVCL_XF92 (HiB5.LV-BA8)CVCL_XF93 (HiB5.pNS-6)CVCL_XF94 (HiB5.pUbi-11)
Sex of cell Sex unspecified
Age at sampling 16FD
Category Conditionally immortalized cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-61.html
Publications

PubMed=1878969; DOI=10.1016/0092-8674(91)90116-g
Renfranz P.J., Cunningham M.G., McKay R.D.G.
Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain.
Cell 66:713-729(1991)

PubMed=12112642; DOI=10.1002/jgm.268
Rosenqvist N., Hard af Segerstad C., Samuelsson C., Johansen J., Lundberg C.
Activation of silenced transgene expression in neural precursor cell lines by inhibitors of histone deacetylation.
J. Gene Med. 4:248-257(2002)

PubMed=22457755; DOI=10.1371/journal.pone.0033352; PMCID=PMC3310062
Subburaju S., Benes F.M.
Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders.
PLoS ONE 7:e33352.1-e33352.10(2012)

Cross-references
Encyclopedic resources Wikidata; Q94208147
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number11