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Cellosaurus HiB5 (CVCL_XF91)

[Text version]
Cell line name HiB5
Accession CVCL_XF91
Resource Identification Initiative To cite this cell line use: HiB5 (RRID:CVCL_XF91)
Comments Characteristics: Proliferates at the permissive temperature (33 Celsius). Differentiates at the restrictive temperature (37 Celsius).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic brain, hippocampus; UBERON=UBERON_0006238+UBERON_0002421.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Hierarchy Children:
CVCL_XF92 (HiB5.LV-BA8)CVCL_XF93 (HiB5.pNS-6)CVCL_XF94 (HiB5.pUbi-11)
Sex of cell Sex unspecified
Age at sampling 16FD
Category Conditionally immortalized cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-61.html
Publications

PubMed=1878969; DOI=10.1016/0092-8674(91)90116-g
Patricia J. Renfranz, Miles Gregory Cunningham, Ronald Davies Graham McKay;
Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain.
Cell 66:713-729(1991)

PubMed=12112642; DOI=10.1002/jgm.268
Nina Rosenqvist, Caroline Hard af Segerstad, Christofer Samuelsson, Jens Johansen, Cecilia Lundberg;
Activation of silenced transgene expression in neural precursor cell lines by inhibitors of histone deacetylation.
J. Gene Med. 4:248-257(2002)

PubMed=22457755; DOI=10.1371/journal.pone.0033352; PMCID=PMC3310062
Sivan Subburaju, Francine Mary Benes;
Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders.
PLoS ONE 7:e33352.1-e33352.10(2012)

Cross-references
Encyclopedic resources Wikidata; Q94208147
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number12