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Cellosaurus MKN45-Cas9-526 (CVCL_XE84)

[Text version]
Cell line name MKN45-Cas9-526
Synonyms MKN-45-Cas9-526
Accession CVCL_XE84
Resource Identification Initiative To cite this cell line use: MKN45-Cas9-526 (RRID:CVCL_XE84)
Comments Population: Japanese.
Characteristics: Transduced with a Cas9-FLAG-Neo construct.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9 (Note=With a C-terminal FLAG tag).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000526

Markers:
AmelogeninX
CSF1PO12
D2S133818
D3S135815,16
D5S81810,11
D6S104314
D7S82010,11
D8S117913,17
D12S39126
D13S3178,11
D16S53910
D18S5116
D19S43314,16.2
D21S1131
FGA19,24
Penta E10
TH017
TPOX8
vWA19

Run an STR similarity search on this cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_XE84
CCRID; 1101HUM-PUMC000526
Encyclopedic resources Wikidata; Q95989939
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number14