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Cellosaurus Li-7-Cas9-754 (CVCL_XE74)

[Text version]
Cell line name Li-7-Cas9-754
Accession CVCL_XE74
Resource Identification Initiative To cite this cell line use: Li-7-Cas9-754 (RRID:CVCL_XE74)
Comments Population: Japanese.
Characteristics: Transduced with a Cas9-FLAG-Neo construct.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9 (Note=With a C-terminal FLAG tag).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3840 (Li-7)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000754

Markers:
AmelogeninX
CSF1PO12
D2S133817,19
D3S135815,16
D5S8189,11
D6S104310,12
D7S82010,11
D8S117913,14
D12S39122,24
D13S31711
D16S5399
D18S5116
D19S43312,14
D21S1130
FGA20
Penta E5,19
TH017
TPOX8,11
vWA16,19

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Cross-references
Cell line databases/resources CCRID; 1101HUM-PUMC000754
Encyclopedic resources Wikidata; Q95982146
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number14