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Cellosaurus NCI-H1299-Luc2-tdT-2 (CVCL_XE62)

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Cell line name NCI-H1299-Luc2-tdT-2
Accession CVCL_XE62
Resource Identification Initiative To cite this cell line use: NCI-H1299-Luc2-tdT-2 (RRID:CVCL_XE62)
Comments Population: Caucasian.
Karyotypic information: Has lost chromosome Y (from parent cell line).
Genetic integration: Method=Transduction; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0060 (NCI-H1299)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000645

Markers:
AmelogeninX
CSF1PO12
D2S133823,24
D3S135817
D5S81811
D6S104311
D7S82010
D8S117910,13
D12S39121,22
D13S31712
D16S53912,13
D18S5116
D19S43314
D21S1132.2
FGA20
Penta E11
TH016,9.3
TPOX8
vWA16,18

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Cross-references
Cell line databases/resources cancercelllines; CVCL_XE62
CCRID; 1101HUM-PUMC000645
Encyclopedic resources Wikidata; Q95993117
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number13