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Cellosaurus KC12 (CVCL_X904)

[Text version]
Cell line name KC12
Synonyms KC 12; KC-12
Accession CVCL_X904
Resource Identification Initiative To cite this cell line use: KC12 (RRID:CVCL_X904)
Comments Population: Japanese.
Doubling time: ~24 hours (PubMed=8105119).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Renal cell carcinoma (NCIt: C9385)
Von Hippel-Lindau syndrome (NCIt: C3105)
Renal cell carcinoma (ORDO: Orphanet_217071)
Von Hippel-Lindau disease (ORDO: Orphanet_892)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 44Y
Category Cancer cell line
Publications

PubMed=8105119; DOI=10.1093/oxfordjournals.jjco.a039638
Kohno T., Sekine T., Tobisu K.-i., Oshimura M., Yokota J.
Chromosome 3p deletion in a renal cell carcinoma cell line established from a patient with von Hippel-Lindau disease.
Jpn. J. Clin. Oncol. 23:226-231(1993)

PubMed=10761702; DOI=10.1111/j.1349-7006.2000.tb00927.x; PMCID=PMC5926323
Yang Z.-Q., Yoshida M.A., Fukuda Y., Kurihara N., Nakamura Y., Inazawa J.
Molecular cytogenetic analysis of 17 renal cancer cell lines: increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas.
Jpn. J. Cancer Res. 91:156-163(2000)

PubMed=11146448; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1034>3.0.CO;2-S
Kondo K.-i., Yao M., Kobayashi K., Ota S., Yoshida M., Kaneko S., Baba M., Sakai N., Kishida T., Kawakami S., Uemura H., Nagashima Y., Nakatani Y., Hosaka M.
PTEN/MMAC1/TEP1 mutations in human primary renal-cell carcinomas and renal carcinoma cell lines.
Int. J. Cancer 91:219-224(2001)

PubMed=22949125; DOI=10.1002/ijc.27822
Pawlowski R., Muhl S.M., Sulser T., Krek W., Moch H., Schraml P.
Loss of PBRM1 expression is associated with renal cell carcinoma progression.
Int. J. Cancer 132:E11-E17(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_X904
CGH-DB; 9334-4
Encyclopedic resources Wikidata; Q54899602
Gene expression databases GEO; GSM374460
Polymorphism and mutation databases Cosmic; 849373
Cosmic; 2520638
Progenetix; CVCL_X904
Entry history
Entry creation05-Sep-2014
Last entry update05-Oct-2023
Version number12