ID   KC12
AC   CVCL_X904
SY   KC 12; KC-12
DR   cancercelllines; CVCL_X904
DR   CGH-DB; 9334-4
DR   Cosmic; 849373
DR   Cosmic; 2520638
DR   GEO; GSM374460
DR   Progenetix; CVCL_X904
DR   Wikidata; Q54899602
RX   PubMed=8105119;
RX   PubMed=10761702;
RX   PubMed=11146448;
RX   PubMed=22949125;
CC   Population: Japanese.
CC   Doubling time: ~24 hours (PubMed=8105119).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C9385; Renal cell carcinoma
DI   NCIt; C3105; Von Hippel-Lindau syndrome
DI   ORDO; Orphanet_217071; Renal cell carcinoma
DI   ORDO; Orphanet_892; Von Hippel-Lindau disease
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   44Y
CA   Cancer cell line
DT   Created: 05-09-14; Last updated: 05-10-23; Version: 12
//
RX   PubMed=8105119; DOI=10.1093/oxfordjournals.jjco.a039638;
RA   Kohno T., Sekine T., Tobisu K.-i., Oshimura M., Yokota J.;
RT   "Chromosome 3p deletion in a renal cell carcinoma cell line
RT   established from a patient with von Hippel-Lindau disease.";
RL   Jpn. J. Clin. Oncol. 23:226-231(1993).
//
RX   PubMed=10761702; DOI=10.1111/j.1349-7006.2000.tb00927.x; PMCID=PMC5926323;
RA   Yang Z.-Q., Yoshida M.A., Fukuda Y., Kurihara N., Nakamura Y.,
RA   Inazawa J.;
RT   "Molecular cytogenetic analysis of 17 renal cancer cell lines:
RT   increased copy number at 5q31-33 in cell lines from nonpapillary
RT   carcinomas.";
RL   Jpn. J. Cancer Res. 91:156-163(2000).
//
RX   PubMed=11146448; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1034>3.0.CO;2-S;
RA   Kondo K.-i., Yao M., Kobayashi K., Ota S., Yoshida M., Kaneko S.,
RA   Baba M., Sakai N., Kishida T., Kawakami S., Uemura H., Nagashima Y.,
RA   Nakatani Y., Hosaka M.;
RT   "PTEN/MMAC1/TEP1 mutations in human primary renal-cell carcinomas and
RT   renal carcinoma cell lines.";
RL   Int. J. Cancer 91:219-224(2001).
//
RX   PubMed=22949125; DOI=10.1002/ijc.27822;
RA   Pawlowski R., Muhl S.M., Sulser T., Krek W., Moch H., Schraml P.;
RT   "Loss of PBRM1 expression is associated with renal cell carcinoma
RT   progression.";
RL   Int. J. Cancer 132:E11-E17(2013).
//