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Cellosaurus ZMAC-1 (CVCL_X750)

[Text version]
Cell line name ZMAC-1
Synonyms UIMAC FBAL-A; FBAL-A; ZMAC; Zuckermann MACrophage-1
Accession CVCL_X750
Resource Identification Initiative To cite this cell line use: ZMAC-1 (RRID:CVCL_X750)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-8764.
Characteristics: CSF1 dependent.
Virology: Susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV) (PubMed=22648044).
Doubling time: ~72 hours (Patent=US9169465).
Derived from site: In situ; Fetal lung, alveolus; UBERON=UBERON_0005597+UBERON_0002299.
Cell type: Alveolar macrophage; CL=CL_0000583.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Landrace x Yorkshire x Duroc; VBO=VBO_0001161+VBO_0001212+VBO_0001127.
Sex of cell Sex unspecified
Age at sampling 58FD
Category Factor-dependent cell line
Web pages Info; -; -; https://www.pork.org/research/a-study-on-the-feasibility-of-using-a-porcine-alveolar-macrophage-cell-line-to-produce-a-prrs-modified-live-virus-vaccine/
Publications

PubMed=22648044; DOI=10.1016/j.vetimm.2012.05.008
Gabriela Calzada-Nova, Robert J. Husmann, William M. Schnitzlein, Federico A. Zuckermann;
Effect of the host cell line on the vaccine efficacy of an attenuated porcine reproductive and respiratory syndrome virus.
Vet. Immunol. Immunopathol. 148:116-125(2012)

Patent=US9169465
Federico A. Zuckermann;
Non-simian cells for growth of porcine reproductive and respiratory syndrome (PRRS) virus.
Patent number US9169465, 27-Oct-2015

PubMed=33268540; DOI=10.1128/jcm.01757-20; PMCID=PMC8106717
Wannarat Yim-im, Hai-Yan Huang, Jie Park, Chong Wang, Gabriela Calzada-Nova, Phillip Gauger, Karen Harmon, Rodger Main, Jian-Qiang Zhang;
Comparison of ZMAC and MARC-145 cell lines for improving porcine reproductive and respiratory syndrome virus isolation from clinical samples.
J. Clin. Microbiol. 59:e01757.20.1-e01757.20.15(2021)

Cross-references
Encyclopedic resources Wikidata; Q54995968
Entry history
Entry creation05-Sep-2014
Last entry update10-Apr-2025
Version number14