ID   ZMAC-1
AC   CVCL_X750
SY   UIMAC FBAL-A; FBAL-A; ZMAC; Zuckermann MACrophage-1
DR   Wikidata; Q54995968
RX   Patent=US9169465;
RX   PubMed=22648044;
RX   PubMed=33268540;
WW   Info; -; -; https://www.pork.org/research/a-study-on-the-feasibility-of-using-a-porcine-alveolar-macrophage-cell-line-to-produce-a-prrs-modified-live-virus-vaccine/
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-8764.
CC   Characteristics: CSF1 dependent.
CC   Virology: Susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV) (PubMed=22648044).
CC   Doubling time: ~72 hours (Patent=US9169465).
CC   Derived from site: In situ; Fetal lung, alveolus; UBERON=UBERON_0005597+UBERON_0002299.
CC   Cell type: Alveolar macrophage; CL=CL_0000583.
CC   Breed/subspecies: Landrace x Yorkshire x Duroc; VBO=VBO_0001161+VBO_0001212+VBO_0001127.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
SX   Sex unspecified
AG   58FD
CA   Factor-dependent cell line
DT   Created: 05-09-14; Last updated: 10-04-25; Version: 14
//
RX   PubMed=33268540; DOI=10.1128/jcm.01757-20; PMCID=PMC8106717;
RA   Yim-im, Wannarat
RA   Huang, Hai-Yan
RA   Park, Jie
RA   Wang, Chong
RA   Calzada-Nova, Gabriela
RA   Gauger, Phillip
RA   Harmon, Karen
RA   Main, Rodger
RA   Zhang, Jian-Qiang
RT   "Comparison of ZMAC and MARC-145 cell lines for improving porcine
RT   reproductive and respiratory syndrome virus isolation from clinical
RT   samples.";
RL   J. Clin. Microbiol. 59:e01757.20.1-e01757.20.15(2021).
//
RX   Patent=US9169465;
RA   Zuckermann, Federico A.
RT   "Non-simian cells for growth of porcine reproductive and respiratory
RT   syndrome (PRRS) virus.";
RL   Patent number US9169465, 27-Oct-2015.
//
RX   PubMed=22648044; DOI=10.1016/j.vetimm.2012.05.008;
RA   Calzada-Nova, Gabriela
RA   Husmann, Robert J.
RA   Schnitzlein, William M.
RA   Zuckermann, Federico A.
RT   "Effect of the host cell line on the vaccine efficacy of an attenuated
RT   porcine reproductive and respiratory syndrome virus.";
RL   Vet. Immunol. Immunopathol. 148:116-125(2012).
//