AC   CVCL_X750
SY   UIMAC FBAL-A; FBAL-A; ZMAC; Zuckermann MACrophage-1
DR   ATCC; PTA-8764
DR   Wikidata; Q54995968
RX   Patent=US9169465;
RX   PubMed=22648044;
RX   PubMed=33268540;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-8764.
CC   Characteristics: CSF1 dependent.
CC   Virology: Susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV) (PubMed=22648044).
CC   Doubling time: ~72 hours (Patent=US9169465).
CC   Derived from site: In situ; Fetal lung, alveolus; UBERON=UBERON_0005597+UBERON_0002299.
CC   Cell type: Alveolar macrophage; CL=CL_0000583.
CC   Breed/subspecies: Landrace x Yorkshire x Duroc.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
SX   Sex unspecified
AG   58FD
CA   Factor-dependent cell line
DT   Created: 05-09-14; Last updated: 29-06-23; Version: 11
RX   Patent=US9169465;
RA   Zuckermann F.A.;
RT   "Non-simian cells for growth of porcine reproductive and respiratory
RT   syndrome (PRRS) virus.";
RL   Patent number US9169465, 27-Oct-2015.
RX   PubMed=22648044; DOI=10.1016/j.vetimm.2012.05.008;
RA   Calzada-Nova G., Husmann R.J., Schnitzlein W.M., Zuckermann F.A.;
RT   "Effect of the host cell line on the vaccine efficacy of an attenuated
RT   porcine reproductive and respiratory syndrome virus.";
RL   Vet. Immunol. Immunopathol. 148:116-125(2012).
RX   PubMed=33268540; DOI=10.1128/jcm.01757-20;
RA   Yim-im W., Huang H.-Y., Park J., Wang C., Calzada-Nova G., Gauger P.,
RA   Harmon K., Main R., Zhang J.-Q.;
RT   "Comparison of ZMAC and MARC-145 cell lines for improving porcine
RT   reproductive and respiratory syndrome virus isolation from clinical
RT   samples.";
RL   J. Clin. Microbiol. 59:e01757.20.1-e01757.20.15(2021).