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Cellosaurus (CVCL_X637)

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Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg158His (c.473G>A); ClinVar=VCV000141963; Zygosity=Homozygous (Cosmic-CLP=753552; DepMap=ACH-002235).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.74
Native American0
East Asian, North71.8
East Asian, South26.84
South Asian0
European, North0
European, South0.61
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=753552

Markers:
AmelogeninX,Y
CSF1PO12
D13S3178,10
D16S53910,12
D5S81811
D7S8209,11
TH019
TPOX8,9
vWA16,17

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Publications




Cancer Cell 33:386-400.e5(2018)

Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number38