Cellosaurus cell line U87.CD4 (CVCL

Cellosaurus U87.CD4 (CVCL_X626)

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Cell line name

U87.CD4

Synonyms

U87/CD4; U87MG.CD4; U87 CD4+

Accession

CVCL_X626

Resource Identification Initiative

To cite this cell line use: U87.CD4 (RRID:CVCL_X626)

Comments

Problematic cell line: Misidentified. Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.

Sequence variations

Mutation; HGNC; HGNC:7765; NF1; Simple; p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT); ClinVar=VCV000420078; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9588; PTEN; Simple; c.209+1G>T; ClinVar=VCV000229705; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).

Disease

Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0022 (U-87MG ATCC)
Children:

CVCL_X627 (U87.CD4.CCR1)	CVCL_X628 (U87.CD4.CCR2)	CVCL_X629 (U87.CD4.CCR3)
CVCL_X630 (U87.CD4.CCR5)	CVCL_X631 (U87.CD4.CCR5.CXCR4)	CVCL_X632 (U87.CD4.CXCR4)

Sex of cell

Male

Age at sampling

Age unspecified