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Cellosaurus SiHa-NTRpuro (CVCL_X529)

[Text version]

Cell line name SiHa-NTRpuro
Accession CVCL_X529
Resource Identification Initiative To cite this cell line use: SiHa-NTRpuro (RRID:CVCL_X529)
Comments Population: Japanese.
Characteristics: Contains a complete HPV16 genome with a disruption of the E2 region and a small deletion (from parent cell line).
Transfected with: UniProtKB; P38489; Escherichia coli nitroreductase nfnB.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from sampling site: Uterus; cervix.
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0032 (SiHa)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line

PubMed=14997211; DOI=10.1038/sj.bjc.6601612
Helsby N.A., Ferry D.M., Patterson A.V., Pullen S.M., Wilson W.R.
2-amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT.
Br. J. Cancer 90:1084-1092(2004)

Encyclopedic resources Wikidata; Q54953472
Entry history
Entry creation05-Sep-2014
Last entry update23-Jun-2022
Version number9