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Cellosaurus HBEC2-KT (CVCL_X490)

[Text version]
Cell line name HBEC2-KT
Synonyms HBEC2 KT; HBEC2KT; HBEC 2-KT; HBEC2 Cdk4-hTERT; HBEC2
Accession CVCL_X490
Resource Identification Initiative To cite this cell line use: HBEC2-KT (RRID:CVCL_X490)
Comments Transfected with: HGNC; 11730; TERT.
Transfected with: MGI; MGI:88357; Cdk4.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_DH91 ! HBEC2-E
Sex of cell Male
Age at sampling 68Y
Category Telomerase immortalized cell line
Publications

PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703
Ramirez R.D., Sheridan S., Girard L., Sato M., Kim Y., Pollack J., Peyton M., Zou Y., Kurie J.M., DiMaio J.M., Milchgrub S., Smith A.L., Souza R.F., Gilbey L., Zhang X., Gandia K., Vaughan M.B., Wright W.E., Gazdar A.F., Shay J.W., Minna J.D.
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Cancer Res. 64:9027-9034(2004)

PubMed=20624269; DOI=10.1186/1756-9966-29-75
Du L.-Q., Schageman J.J., Irnov I., Girard L., Hammond S.M., Minna J.D., Gazdar A.F., Pertsemlidis A.
MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs.
J. Exp. Clin. Cancer Res. 29:75.1-75.12(2010)

Cross-references
Encyclopedic resources Wikidata; Q54881394
Gene expression databases GEO; GSM171893
GEO; GSM253436
GEO; GSM794408
Entry history
Entry creation05-Sep-2014
Last entry update30-Jan-2024
Version number18