ID   HBEC2-KT
AC   CVCL_X490
SY   HBEC2 KT; HBEC2KT; HBEC 2-KT; HBEC2 Cdk4-hTERT; HBEC2
DR   GEO; GSM171893
DR   GEO; GSM253436
DR   GEO; GSM794408
DR   Wikidata; Q54881394
RX   PubMed=15604268;
RX   PubMed=20624269;
CC   Transfected with: HGNC; 11730; TERT.
CC   Transfected with: MGI; MGI:88357; Cdk4.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: miRNA expression profiling.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_DH91 ! HBEC2-E
SX   Male
AG   68Y
CA   Telomerase immortalized cell line
DT   Created: 05-09-14; Last updated: 30-01-24; Version: 18
//
RX   PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703;
RA   Ramirez R.D., Sheridan S., Girard L., Sato M., Kim Y., Pollack J.,
RA   Peyton M., Zou Y., Kurie J.M., DiMaio J.M., Milchgrub S., Smith A.L.,
RA   Souza R.F., Gilbey L., Zhang X., Gandia K., Vaughan M.B., Wright W.E.,
RA   Gazdar A.F., Shay J.W., Minna J.D.;
RT   "Immortalization of human bronchial epithelial cells in the absence of
RT   viral oncoproteins.";
RL   Cancer Res. 64:9027-9034(2004).
//
RX   PubMed=20624269; DOI=10.1186/1756-9966-29-75;
RA   Du L.-Q., Schageman J.J., Irnov I., Girard L., Hammond S.M., Minna J.D.,
RA   Gazdar A.F., Pertsemlidis A.;
RT   "MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells
RT   and suggests a possible pathological relationship between SCLCs and
RT   NSCLCs.";
RL   J. Exp. Clin. Cancer Res. 29:75.1-75.12(2010).
//